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Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors during the central nervous system, conolidine modulates alternate molecular targets. A Science Advances analyze observed that conolidine interacts Together with the atypical chemokine receptor ACKR3/CXCR7,

Conolidine’s analgesic outcomes stem from its interaction with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors in the central anxious process, conolidine modulates alternate molecular targets. A Science Improvements review discovered that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, whic